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Invasive Fungal Infection Masquerading as Meningioma

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33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

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Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.

Invasive Fungal Infection Masquerading as Meningioma

by: Cassandra Voong, MD; Hasan Samra, MD

33-year-old female with a past medical history of chronic sinusitis presented with complaints of progressively worsening headaches, nausea, vomiting and diminished visual acuity. MRI brain shows a large anterior extra-axial lobulated mass with homogeneous contrast-enhancement that was concerning for invasive olfactory meningioma. She underwent a bifrontal craniotomy for tumor resection and the biopsied specimen was sent for pathology. Her symptoms improved after the surgery. Surprisingly, the biopsy suggested a fungal etiology of the brain lesion and PCR testing performed on a histopathology tissue block confirmed the fungal elements to be of Curvularia or Bipolaris species (dematiaceous mold). Infectious disease was consulted, and the patient was started on voriconazole.